SCIEX
API 3000
Provisional entry — research in progress
This page was generated automatically from cited public sources and hasn't completed the full research pass yet. Every specification shown carries its source; more detail is added as research completes.
The SCIEX API 3000 is a triple quadrupole mass spectrometer. The SCIEX API 3000 uses turbo-molecular pumping. The SCIEX API 3000 was introduced in 1998 as part of the replacement of the cryopump API III platform.[1]
Plate 01Applied Biosystems API 3000 LC-MS Walk-around
RichmondScientificWatch on YouTubePlate 02ScieX API 3000
Prodigy ScientificWatch on YouTubePlate 03AB MDS SCIEX API 3000 Triple Quadrupole LC Mass Spectrometer 018444 Pred to 4000 - 10433
WWW.BOSTONIND.COM | Laboratory & Scientific Lab Equipment | Boston Industries, Inc.Watch on YouTubePlate 04PE SCIEX API 3000 LC/MS/MS System ID 13825
The Lab World GroupWatch on YouTubePlate 05PE SCIEX API 3000 LC/MS/MS System ID 13816
The Lab World GroupWatch on YouTubePlate 06PE SCIEX API 3000 LC/MS/MS System ID 13815
The Lab World GroupWatch on YouTubePlate 07ABI MDS Sciex 018444 API 3000 Triple Quad Mass Spectrometer LC-MS Pred. API4000 - 9827
WWW.BOSTONIND.COM | Laboratory & Scientific Lab Equipment | Boston Industries, Inc.Watch on YouTube
Produced
1998–
Power
207-242 VAC, 15 A, single phase[3]
Vacuum
220 VAC at 13–15 A (nominal)[3]
Gas delivery
Curtain Gas interface[2]
What it is
How it works
General reference — not yet source-verifiedA triple quadrupole mass spectrometer uses three sequential quadrupole mass analyzers. The first quadrupole selects ions of a specific mass-to-charge ratio. The second quadrupole acts as a collision cell where selected ions are fragmented by collision with gas molecules. The third quadrupole analyzes the resulting fragment ions.
Applications
The API 3000 is applied to protein and peptide analysis, small molecule analysis for drug metabolism and pharmacokinetic studies, and cassette dosing experiments. The system supports routine high-throughput analysis of hundreds of samples per day.[2][6]
- mass spectrometry
- liquid chromatography-mass spectrometry (LC-MS)
What do the numbers mean?
Power & electrical2
- Electrical Requirement (Main Power)
- 207–242 VAC, 50/60 Hz, 15 A per circuit, two circuits required[3]
Vacuum & pumping6
Gas & chemistry6
Control & software2
Dimensions & facilities2
Configuration & options10
Vintage & configurations
- 1998Production start[1]
In 1998, the cryopump API III platform began to be replaced with turbo-molecular-pumped single and triple quadrupole mass spectrometer products that evolved from the API 2000 (benchtop) and API 3000 to the current API 7500 series.
What replaced it?
Alternatives
Tools documented as functional equivalents — same process step and wafer size, from a different manufacturer. Each equivalence cites its source.
- Agilent 6470 Triple Quadrupole LC-MS— Same function class: Precision Optics, nullCompare in depthsource[5]
Related models
- siblingSCIEX API 2000— The source groups API 2000 and API 3000 together as products that evolved into the current API 7500 series.source[1]
What does it need to run?
Site utility requirements, footprint, and infrastructure needed to install and operate this tool. Sourced from public records.
- product family contextturbo-molecular-pumped single and triple quadrupole mass spectrometer products[1]
- Ionization SourceAtmospheric Pressure Ionization (API) with TurboIonSpray and Heated Nebulizer (APCI) options[3]
- Interface TechnologyCurtain Gas interface[2]
- Electrical Requirement (Main Power)207–242 VAC, 50/60 Hz, 15 A per circuit, two circuits required[3]
- Power Consumption (Mass Spectrometer + Roughing Pump)220 VAC at 13–15 A (nominal)[3]
- Curtain Gas RequirementUHP N2 (99.999%) at 60 psig, flow up to 3.5 L/min[3]
- Gas 1 Requirement (Nebulizer/Auxiliary)Zero air or UHP N2 (99.999%) at 90 psig, flow up to 4.0 L/min[3]
- Gas 2 Requirement (Heater/Nebulizer)Zero air or UHP N2 (99.999%) at 90 psig, flow up to 8.0 L/min[3]
- Source Exhaust Gas RequirementClean, dry, oil-free air at 50 psig, flow up to 8.0 L/min[3]
- Pumping technologyturbo-molecular-pumped[1]
- Ionization methodAtmospheric Pressure Ionization (API)[3]
- Electrical requirements207-242 VAC, 15 A, single phase[3]
- Gas 1 (nebulizer) supplyZero air or UHP N2 at 90 psig, up to 4 L/min[3]
- Curtain/CAD gas supplyUHP N2 at 60 psig, up to 3.5 L/min[3]
Where are the manuals?
Generated from public-source data on file. Enter your email to access — nothing is published; details are routed privately.
Not publicly documented
Field notes
No research found yet — worked with this tool? Share what you know.
Frequently asked questions
What type of mass spectrometer is the SCIEX API 3000?
The API 3000 is a triple quadrupole mass spectrometer (LC/MS/MS system) from Applied Biosystems/MDS SCIEX.[4][6]
What collision cell technology does the API 3000 use?
The API 3000 uses LINAC collision cell technology, which provides fast scan times without compromising sensitivity or mass spectral quality.[2]
Not publicly documented
The following facts about the API 3000 are absent from this record as of this revision. First-hand knowledge or a citation closes a gap; every submission is reviewed before publication.
No publicly documented variants, configuration options, or revision breakpoints of the API 3000 are on record.
Answerable by: an OEM product catalog or an engineer who ordered or specified the tool
The control-system platform and OS era of the API 3000 are not on record.
Answerable by: an engineer who operated it or OEM installation records
No publicly documented failure modes or field errata for the API 3000 are on record.
Answerable by: a field service engineer, process engineer, or maintenance technician
The process node or technology generation of the API 3000 is not on record.
Answerable by: an OEM datasheet or a fab qualification report
No publicly documented compatible parts, consumables, or accessories for the API 3000 are on record.
Answerable by: an OEM parts catalog or a service engineer
No research found yet — worked with this tool? Share what you know.
Sources & citations
Sources (6)Every fact above is drawn from these public sources
- [1]en.wikipedia.org — en.wikipedia.orgen.wikipedia.org
- [2]triadsci.com — triadsci.comtriadsci.com
- [3]cdn.labwrench.com — cdn.labwrench.comcdn.labwrench.com
- [4]shop.labexchange.com — shop.labexchange.comshop.labexchange.com
- [5]spectralabsci.comspectralabsci.com
- [6]Sciex API 3000 LCMS triple quadrupole mass spectrometer | 100453 — fischer-analytics.comfischer-analytics.com
Last updated Sep 30, 2026.
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