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SCIEX

API 2000

Precision OpticsIntroduced Produced 1998–SCIEX API 2000 family
Research Quality: 60% complete

Provisional entry — research in progress

This page was generated automatically from cited public sources and hasn't completed the full research pass yet. Every specification shown carries its source; more detail is added as research completes.

The SCIEX API 2000 is a benchtop mass spectrometer that replaced the cryopump-based API III platform in 1998. The API 2000 is a turbo-molecular-pumped instrument available as either a single or triple quadrupole system.[1]

SCIEXAPI 2000
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  • Plate 01AB Sciex API 2000 Spectrometer [BOSTONIND] - 13433

    WWW.BOSTONIND.COM | Laboratory & Scientific Lab Equipment | Boston Industries, Inc.Watch on YouTube
  • Plate 02API 2000 Calculations: Part 2 - PEMY Consulting (Phil Myers)

    PEMY ConsultingWatch on YouTube

Produced

1998–

Vacuum

turbo-molecular-pumped[1]

Preceded by
First in line
This tool
API 2000
Succeeded by
API 7500
All related

What it is

The API 2000 belongs to the SCIEX family of analytical instruments.[1]

How it works

The API 2000 is a triple quadrupole mass spectrometer.[2][4]

Where it fits in the process flow

General reference — not yet source-verified

The API 2000 sits in the analytical measurement part of a laboratory workflow after chromatographic separation and before data interpretation.

Applications

SCIEX makes mass spectrometry instrumentation used in biomedical and environmental applications.[1]

  • mass spectrometry

What do the numbers mean?

Power & electrical1

Power Requirements
2 separate 207 V minimum to 242 V maximum, 15 A grounded single phase circuit[3]
Accurate?

Vacuum & pumping2

pumping platform
turbo-molecular-pumped[1]
Accurate?
Pump Technology
Turbo-molecular pump (successor to cryopump API III)[1]
Accurate?

Dimensions & facilities2

Footprint (Width x Depth x Height)
104 cm x 50 cm x 64 cm[3]
Accurate?
Weight
111 kg (244 lb)[3]
Accurate?

Configuration & options14

form factor
benchtop[1]
Accurate?
instrument type
single and triple quadrupole mass spectrometer products[1]
Accurate?
Mass Range
m/z 5-1,800[3]
Accurate?
Dynamic Range
1 cps to 4x10^6 cps (pulse counting)[3]
Accurate?
Scan Speed
up to 2400 amu/sec[3]
Accurate?
Collision Cell
LINAC collision cell[3]
Accurate?
Type
Benchtop single or triple quadrupole mass spectrometer[1]
Accurate?
Introduced
1998[1]
Accurate?
instrument type
LC/MS/MS system[4]
Accurate?
instrument type
mass spectrometer[2]
Accurate?
mass analyzer
triple quadrupole[5]
Accurate?
description
enhanced high performance triple quadrupole mass spectrometer[5]
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applications
protein and peptide analysis[5]
Accurate?
applications
small molecule analysis in drug metabolism and pharmacokinetic studies[5]
Accurate?

Vintage & configurations

  1. 1998platform evolution reference[1]

    In 1998, the cryopump API III platform began to be replaced with turbo-molecular-pumped single and triple quadrupole mass spectrometer products that evolved from the API 2000 and API 3000 to the API 7500 series.

  2. 1998-01-01Production start[2]

    Sales start

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What replaced it?

  • successorSCIEX API 7500— The API 7500 series evolved from the API 2000 product line.source[1]
  • siblingSCIEX API 3000— The source groups API 2000 and API 3000 together as products that evolved into the current API 7500 series.source[1]

What does it need to run?

Site utility requirements, footprint, and infrastructure needed to install and operate this tool. Sourced from public records.

  • pumping platformturbo-molecular-pumped[1]
  • Power Requirements2 separate 207 V minimum to 242 V maximum, 15 A grounded single phase circuit[3]
  • Pump TechnologyTurbo-molecular pump (successor to cryopump API III)[1]

Where are the manuals?

Generated from public-source data on file. Enter your email to access — nothing is published; details are routed privately.

Not publicly documented

Field notes

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Frequently asked questions

When was the SCIEX API 2000 introduced?

The SCIEX API 2000 was introduced in 1998.[2]

What type of mass analyzer does the API 2000 use?

The API 2000 uses a triple quadrupole mass analyzer.[5][2]

Which company manufactured the API 2000?

The API 2000 was manufactured by the AB Sciex joint venture between Applied Biosystems and MDS Sciex.[2][4][1]

Is the API 2000 a benchtop instrument?

Yes, the API 2000 is a benchtop system.[1]

Not publicly documented

The following facts about the API 2000 are absent from this record as of this revision. First-hand knowledge or a citation closes a gap; every submission is reviewed before publication.

  • No publicly documented variants, configuration options, or revision breakpoints of the API 2000 are on record.

    Answerable by: an OEM product catalog or an engineer who ordered or specified the tool

  • The control-system platform and OS era of the API 2000 are not on record.

    Answerable by: an engineer who operated it or OEM installation records

  • No publicly documented failure modes or field errata for the API 2000 are on record.

    Answerable by: a field service engineer, process engineer, or maintenance technician

  • The process node or technology generation of the API 2000 is not on record.

    Answerable by: an OEM datasheet or a fab qualification report

  • No publicly documented compatible parts, consumables, or accessories for the API 2000 are on record.

    Answerable by: an OEM parts catalog or a service engineer

No research found yet — worked with this tool? Share what you know.

Sources & citations

Sources (5)Every fact above is drawn from these public sources
  1. [1]en.wikipedia.org — en.wikipedia.orgen.wikipedia.org
  2. [2]mass-spec-capital.com — mass-spec-capital.commass-spec-capital.com
  3. [3]shop.labexchange.comshop.labexchange.com
  4. [4]mass-spec-capital.com — mass-spec-capital.commass-spec-capital.com
  5. [5]spectralabsci.com — spectralabsci.comspectralabsci.com
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Last updated Oct 5, 2026.

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